Objective The Notch signaling regulates numerous cell growth,differentiation,and death.In particular,transmembrane receptor Delta-like 4(Dll4)has raised extensive interests since it is absolutely requ
Objective Fatty acid is the main organic molecule composing the cell membrane,and thus is critical with both the energy and materials necessary for the biosynthesis of signaling molecule.
目的 肺癌是全世界癌症相关死亡最常见的原因，其中超过85％的肺癌是非小细胞肺癌。据统计，高达69％的晚期非小细胞肺癌患者可能有一个潜在的可操作的分子靶点。临床上成纤维细胞生长因子受体1(FGFR1)和SOX2 高表达与非小细胞肺癌患者生存时间短呈正相关。
Objective GBC is the most common malignancy of the biliary tracts1.The incidence and distribution of GBC differ across worldwide.For example,the prevalence of GBC in South and East Asia is considerabl
目的 目的：研究胶质瘤中TERT 突变、染色体1p/19q 联合缺失与临床预后的关系。方法 方法：采用荧光原位杂交法(Fluorescence in situ hybridization,FISH)检测1p/19q联合缺失情况；采用PCR 技术检测TERT 基因突变；同时收集免疫组化方法对IDH1、MGMT、Ki-67 表达情况的检测结果。
Objective Lung cancer is the leading cause of cancer death worldwide.In the past decades,significant improvements have been made for lung cancer treatment,based on discoveries of molecular biomarkers
Objective Acute myeloid leukemia(AML)is a common hematologic malignance with strong heterogeneity,different cytogenetic and molecular defects present completely different clinical properties and thera
目的 探讨原发性肺肉瘤样癌(PSC)的CT 征象特点及病理学特点，提高对该病的认识及影像诊断水平。方法 回顾性分析陕西省肿瘤医院2014 年1 月-2018 年10 月病理确诊的30 例原发性肺肉瘤样癌(PSC)患者的临床、影像资料，并与病理结果进行对照分析。
目的 小肠内分泌肿瘤(neuroendocrine tumor,NET)起源于消化道中的肠嗜铬细胞,其临床表现以类癌综合征为主,如面部潮红、腹泻、哮喘等,尤其是肠系膜纤维化。既往研究表明,小肠NET病程似乎比腺癌更为良性,但因其临床症状具有非特异性,且肿瘤相关症状发生较晚,发生远处转移比例较多,多数患者就诊时已失去手术根治机会,预后不佳。目前小肠NET 的5 年生存率低于50％。因此,进一步了解本