论文部分内容阅读
Molecular hybridisation approach is an emerging tool in designing new drug molecules.
Conjugates of Coumarin with Benzimidazole as Potential Antibacterial Agents
【摘 要】
：
Molecular hybridisation approach is an emerging tool in designing new drug molecules.
【机 构】
：
Medicinal and Process Chemistry Division,CSIR-Central Drug Research Institute,BS-10/1,Sector 10,Jank
【出 处】
：
2015年全国药物化学学术会议暨第五届中英药物化学学术会议
【发表日期】
：
2015年3期
其他文献
Synthesis of N-(4-((1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)-3-fluorophenyl)picolinamide derivatives as c-
c-Met is a proto-oncogene that encode a protien known as hepatocyte growth factor receptor(HGFR)[1].Inappropriate activity of c-Met can cause wide variety of different cancers such as breast,pancreas,
Hemagglutinin(HA)which is essential for influenza viral infection and replication has become a target for the design of anti-influenza drugs.A novel series of oligothiophene compounds focused on the t
Design and Synthesis of Chiral Binaphthol-Derived Bisphosphoric Acids and Their Application in the C
Chiral BINOL-based phosphoric acids are an array of privileged and bifunctional organocatalysts,the activities of which have been successfully demonstrated in a variety of organic transformations.[1]
Bacterial resistance continues to progress and pose a significant threat,both in hospitals and,more recently,in the community.
A series of novel 3-aminothiazolquinolones as newly structural antibacterial agents were designed and synthesized for the first time.
Hybrids of metronidazole and quinolones as antimicrobial agents were developed and their bioactive assay that the newly synthesized compounds exhibited good or even stronger antimicrobial activities a
Berberine-derived Benzimidazoles as New Potential Antimicrobial Agents:Design,Synthesis and Biologic
A series of novel berberine-derived benzimidazole derivatives and characterized by NMR,IR,MS and HRMS spectra.All the new compounds were screened for their antimicrobial efficacy against four Gram-pos
A series of naphthalimide nitrogen mustards as anticancer agents were developed,their structures were characterized by 1H NMR,13C NMR,IR,MS and HRMS spectra,and the single crystal of compound 4g was s
Infectious diseases caused by microbes are a serious public safety issues associated with significant mortality and health-care costs in world-wide.Hence,the development of alternative novel drugs is