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Objective To access the role of dynamic disequilibrium in intervertebral disc degeneration with MR diffusion tensor imaging.Materials and Methods A total of 52 patients with 89 degenerated lumbar intervertebral discs and 20 healthy volunteers with 32 normal lumbar intervertebral discs were enrolled.Degenerated discs were divided into four groups(Ⅱ,Ⅲ,Ⅳ,Ⅴ),corresponding to four degenerated levels from minor to severe defined by Pffirmann grading.Normal discs from healthy volunteers were divided into two groups according to the age of volunteers: Younger group(under 18 years old)and elder group(above 18 years old).