Objective The insulin receptor gene(INSR)undergoes alternative splicing to give rise to two functionally related but also distinct isoforms IR-A and IR-B,which dictate proliferative and metabolic regu
Objective Diffuse gliomas are the most common type of primary brain tumors in central nervous system(CNS),according to the 2016 WHO classification of CNS tumors,diffuse gliomas are generally categoriz
Objective Breast cancer is a major cancer type in women.Protein Kinase D(PKD)family,a family of serine/threonine kinases,includes three family members of PKD1,PKD2 and PKD3.
Objective Cisplatin is the major chemotherapeutic drug in gastric cancer,especially for advanced gastric cancer.The tumor cells often develop resistance to chemotherapeutic drugs,which seriously affec