The particle structure of human T-cell leukemia virus type 1(HTLV-1) is poorly characterized.Here,we have used cryo-electron tomography to analyze HTLV-1 partic
Neuronal synapses are key communication devices in brain circuits.Within the synapse,various subcellular components form highly ordered yet dynamic structure to
Mediator complex plays an essential role in regulation of eukaryotic transcription.The Saccharomyces cerevisiae core Mediator comprises 21 subunits,which are or
Objective: To study the molecular mechanism for the pathogenesis of High-altitude polycythemia(HAPC)in Tibetans.Methods: ultrastructural,histopathological a
A hypoxic environment aggravates the injury for intestinal mucosal barrier(IMB)in altitude residents and promotes bacterial and endotoxin translocation.Howe
Human gut microbiota is largely similar among various populations,but differences in the species and/or strain compositions do exist,and a close relationshi
Aim Colonic air bubbles associated with lavage solution are common and obscure mucosal visibility during colonoscopy.We aimed to determine whether adding si