HSP90 Inhibition Is a Novel Therapeutic Strategy in Gastrointestinal Stromal Tumor

来源 :第十二届全国酶学学术讨论会 | 被引量 : 0次 | 上传用户：hackxingxing

【摘要】

：

　　Gastrointestinal stromal tumor(GIST)is the most common sarcoma of the gastrointestinal tract.Oncogenic KIT or PDGFRA receptor tyrosine kinase mutations are

【作者】

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Jiaqing Zhu Minmin Lu Quan He Lili Liu Yuehong Wu Sheng Qing Wen-Bin Ou

【机构】

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CollegeofLifeSciences,ZhejiangSci-TechUniversity,Hangzhou,Zhejiang,ChinaCollegeofLifeSciences,Zhejia

【出处】

：

第十二届全国酶学学术讨论会

【发表日期】

：

2015年10期

【关键词】

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GIST HSP90 resistance imatinib

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　　Gastrointestinal stromal tumor(GIST)is the most common sarcoma of the gastrointestinal tract.Oncogenic KIT or PDGFRA receptor tyrosine kinase mutations are compelling therapeutic targets in GISTs,and the KIT/PDGFRA kinase inhibitor,imatinib/sunitinib,is standard of care for patients with metastatic GIST

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HSP90 Inhibition Is a Novel Therapeutic Strategy in Gastrointestinal Stromal Tumor

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