A Human Stem Cell Model of Werner Syndrome Reveals Novel Genomic and Epigenomic DysregulationDuringA

来源 :中国细胞生物学学会2015年全国学术大会 | 被引量 : 0次 | 上传用户：mixcenter

【摘要】

：

　　Werner syndrome (WS) is a premature aging disorder caused by genetic mutations in the RecQ DNA helicase WRN.The molecular programs leading to WS-associated

【作者】

：

Weiqi Zhang Guang-Hui Liu

【机构】

：

NationalLaboratoryofBiomacromolecules,InstituteofBiophysics,ChineseAcademyofSciences,Beijing100101,C

【出处】

：

中国细胞生物学学会2015年全国学术大会

【发表日期】

：

2015年4期

【关键词】

：

stem cell senescence Werner syndrome

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　　Werner syndrome (WS) is a premature aging disorder caused by genetic mutations in the RecQ DNA helicase WRN.The molecular programs leading to WS-associated tissue degeneration remain unclear.

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A Human Stem Cell Model of Werner Syndrome Reveals Novel Genomic and Epigenomic DysregulationDuringA

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