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  5. Effects of E2HSA, a Long-Acting GLP-1R Agonist, on Glycemic Control and Beta Cell Function in Diabet

Effects of E2HSA, a Long-Acting GLP-1R Agonist, on Glycemic Control and Beta Cell Function in Diabet

来源 :The 6th China-Russia International Conference on Medicine(第六 | 被引量 : 0次 | 上传用户：bxz231
【摘 要】
：
Aim: E2HSA, a recobinant protein of exendin-4 and human serum albumin, is a long-acting GLP-1 analogue.This study aims to evaluate its hypoglycemic effect and duration, and investigate its potential b
【作 者】
：
Shaocong Hou Caina Li Shuainan Liu Qian Jiang Chunming Jia Zhufang Shen 
【机 构】
：
Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College,Beij
【出 处】
：
The 6th China-Russia International Conference on Medicine(第六
【发表日期】
：
2014年3期
【关键词】
：
E2HSA diabetes β cell 
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Aim: E2HSA, a recobinant protein of exendin-4 and human serum albumin, is a long-acting GLP-1 analogue.This study aims to evaluate its hypoglycemic effect and duration, and investigate its potential benefits on β cell function.Methods: In normal ICR mice, E2HSA was injected subcutaneously at the doses of 1, 3 and 9 mg/kg, respectively.
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