目的：探讨三七总皂苷(Panax Notoginseng Saponins,PNS)对乙酰胆碱(Acetocholine,ACh)-氯化钙(CaC12)诱导的大鼠房颤及期前收缩的干预作用.方法：ACh-CaCl2混合液为造模药物,ACh剂量为66μg/ml,CaCl2剂量为10mg/ml,混合后以尾静脉注射(1 ml/kg)的方式建立房颤动物模型.采用DSI植入式动态心电图分析仪监测实验大鼠24小
Objective: To investigate the inhibitory effects of ginsenoside Re on intimal hyperplasia in balloon-injuried rats and further explore the role of TGF-β1/Smads signaling pathway in this protection.Met
Multi-target drugs, such as cocktail therapy used for treating AIDS, usually show strong efficacy than single-target drugs in treating complicated diseases.This review will mainly focus on ginsenoside
大豆异黄酮是大豆生长过程中形成的一类次级代谢产物,主要含有染料木素(Genistein,GS)、大豆苷元(Daidzein)、大豆苷(Daidzin)和染料木苷(Genistin)4种成分,其中GS为异黄酮类物质中含量最丰富且生物活性最高的一种,又称金雀异黄素、染料木黄酮、5,7,4-三羟基异黄酮.由于其能竞争性结合雌激素受体发挥雌激素样作用,故又被称为植物雌激素.GS具有多种生物学活性,如抗肿瘤
枸杞子是我国的传统名贵中药材,它在我国传统医学中具有重要的地位,其药用价值备受历代医家的推崇。枸杞子补益作用与其中含有的生物活性物质枸杞多糖(Lycium barbarum polysaccharide, LBP)有很大关系。根据检索的文献可见,从中医到西医,从国内到国外,枸杞多糖都是近年来研究枸杞药理和保健作用的主要点。现代科学研究表明,枸杞多糖具有调节免疫、清除自由基、抑制肿瘤、延缓衰老、降血
Aim The present study aimed to investigate the relationship between Wnt/β-catenin and Nrf2 signaling pathways, and understanding the mechanisms underlying the process of inflammatory in chronic obstru
Background and Purpose: Epithelial-mesenchymal transition (EMT) is a phenotype conversion that plays a critical role in the development of pulmonary fibrosis (PF).It is known that a transcription fact
Objective: To investigate the effect of Dendrobium nobile Lindl.Alkaloids (DNLA) on learning and memory deficits of rats induced by injecting streptozotocin (STZ) into intracerebroventricular (ICV), a
Objective: Beta-amyloid (Aβ) deposition and associated neuroinflammation are considered as important factors leading to cognitive deficits in Alzheimers disease (AD).Icariside Ⅱ (ICS Ⅱ) is one of the
Until now, there is not yet antitumor drug with dramatically improved efficacy on non-small cell lung cancer (NSCLC).Marine organism is a rich source of novel compounds with various activities.We isol