• 不 限
  • 期刊论文
  • 硕博论文
  • 会议论文
  • 报 纸
  • 英文论文
  2. 您的位置
  3. 首页
  4. 会议论文
  5. Preventive effects of andrographolide on the development of diabetes in autoimmune diabetic NOD mice

Preventive effects of andrographolide on the development of diabetes in autoimmune diabetic NOD mice

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：chenyinan
【摘 要】
：
Aim: Andrographolide, as an active component in traditional anti-diabetic herbal plants, is a diterpenoid lactone isolated from Andrographis paniculata promising for its potent anti-inflammatory and h
【作 者】
：
Cheng-liang ZHANG Ling GUI Yan-jiao XU Tao WU Dong LU 
【机 构】
：
Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and
【出 处】
：
The 12th Meeting of the Asia Pacific Federation of Pharmacol
【发表日期】
：
2013年4期
【关键词】
：
andrographolide autoimmune diabetes Th1 Th2 Th17 
下载到本地 , 更方便阅读
下载此文 赞助VIP
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Aim: Andrographolide, as an active component in traditional anti-diabetic herbal plants, is a diterpenoid lactone isolated from Andrographis paniculata promising for its potent anti-inflammatory and hypoglycemic effects.However, the effect of andrographolide on the development of diabetes in autoimmune diabetic NOD (non-obese diabetic) mice still remains unknown.This study aims to investigate the protective effects of andrographolide on the development of autoimmune diabetes and further clarify the underlying mechanism.
其他文献
Changes of different sites of skeleton in Lewis rats with type Ⅱ collagen-induced arthritis (CIA)
Aim: It is evident for rheumatoid arthritis (RA) to induce osteoporosis during its development and treatment.However the mechanism of how RA induces osteoporosis is not yet clear.In order to know the
会议
osteroporosisrheumatoid arthritiscollagen-induced arthritishistomorphometryb
Effect of Compound K on enhancing insulin secretion in MIN6 pancreatic β-cells by upregulation of GL
Aim: Compound K (CK) is a final intestinal metabolite of protopanaxadiol-type ginsenosides from Panax ginseng and shows various bioactivities.Although it has also been found to have the property of an
会议
Compound Kinsulin secretionATPGLUT2
Ginsenoside Rg1 promote the proliferation of mesenchymal stem cell in bone marrow and peripheral blo
Aim: We previously demonstrate that ginsenoside Rg1 can improve the hematopoietic function (Eur J Pharmacol, 2012).The current study further investigates the effect of ginsenoside Rg1 on the prolifera
会议
ginsenoside Rg1MSCsproliferationmicroenvironment
The proteasome inhibitor MG132 enhances LDL uptake in hepatocytes through regulating LDLR and PCSK9
Aim: The low-density lipoprotein receptor (LDLR), a determinant regulator in cholesterol homeostasis, is tightly regulated in liver cells.Previous studies demonstrated that the degradation of LDLR is
会议
Low-density lipoprotein receptorproprotein convertase subtilisin/kexin type 9p
Salvianolic acid A protects against diabetic nephropathy in type 2 diabetes
Aim: Salvianolic acid A (SalA) is one of the main water-soluble active components in Salvia miltiorrhizae.The aim of this study was to investigate the effects of SalA on prevention and treatment of di
会议
salvianolic acid Atype 2 diabetesdiabetic nephropathy
Asiatic acid inhibits transforming growth factor-β1-induced collagen expression in keloid fibroblast
Aim: To investigate the effects of asiatic acid (AA) on cell proliferation, invasion and collagen expression in TGF-β1-stimulated keloid fibroblasts and the underlying mechanisms.Methods: 5-ethynyl-2-
会议
asiatic acidkeloid fibroblastsTGF-β/Smad pathwayPPAR-γ
The effect of HeiJiangDan Ointment intervention on cell apoptosis and vascular injury during radiati
Aim: HeiJiangDan is an in-hospital preparation which has the function of clearing toxic and activating blood.It derived from JiZiLuanFaGao which was first recorded in the book of ChuanXinShiYongFang e
会议
radiation dermatitiscell apoptosisHeijiangdan Ointmentvascular injurytraditi
Hepatoprotetive effects of saponins from Panax japonicus against alcohol-induced liver injury via in
Aim: To investigate the protective effects of saponins from Panax japonicus (SPJ) on alcohol-induced hepatic injury and the potential mechanisms involved.Methods: SPJ (200 and 400 mg/kg) were given in
会议
saponins from Panax japonicusalcohol-induced liver injurytoll-like receptor-4
Effects and mechanisms of total glueosides of paeoniflorin derivatives (CP-25) on collagen-induced a
Aim: According to the changes that secondary paw swelling, polyarthritis index, and histological morphological of collagen-induced arthritis (CIA) rats, the antiinflammatory and immunoregulation activ
会议
collagen induced arthritisCP-25paeoniflorintotal glucosides of paeonylymphoc
Immunoregulation effects of polysaccharides isolated from Panax japonicus in immunosuppressed mice
Aim: Rhizoma Panax japonicus (PJ), belonging to Panax species of Araliaceae, has been used to treat a variety of diseases as a folk medicine.Panax japonicus polysaccharides, an activity substance isol
会议
Panax japonicus polysaccharidesimmunosuppressionlymphocytecyclophosphamide