Profiling of Small Noncoding RNAs in Mouse Oocyte and Early Embryos

来源 :中国细胞生物学学会2015年全国学术大会 | 被引量 : 0次 | 上传用户：Mr_Zhou

【摘要】

：

Small non-coding RNAs (ncRNA) play important roles in diverse cellular processes, but little is known about their identities and expression dynamics during fertilization and early embryonic developmen

【作者】

：

Qiyuan Yang Jimin Lin Miao Liu Ronghong Li Xue Zhang Changgen Shi Ya Zhao HuiJuan Shi Ligang Wu

【机构】

：

State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Inst

【出处】

：

中国细胞生物学学会2015年全国学术大会

【发表日期】

：

2015年4期

【关键词】

：

oocyte zygote embryo small non-coding RNA miRNA non-template adenosines adding M

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

其他文献

Mutant p53 accumulated in arsenic-induced EMT in vitro results in metabolic disorder

Carcinogenesis by chronic exposure to arsenic in the environment has been widely concerned.However, the mechanism of cancer formation and progression induced by chronic arsenic exposure is still not c

会议

mutant p53arsenic-inducedEMTmetabolic disorder

A novel PKCε-Smad2/3 signaling contributes to Warburg effect by up-regulating glycolytic gene expres

Cancer cells use aerobic glycolysis preferentially for energy provision, and this metabolic change is critical for tumor growth.Smad2 and Smad3 are components of the transforming growth factor β (TGF-

会议

Prostate cancerglycolysisSmad2/3PKCε

IRF7 promotes the proliferation of human bladder cancer cells

The transcription factor of Interferon Regulatory Factor 7 (IRF7) is not only involved in immune responses but also oncogenesis, and the regulation of oncogenesis is cell type dependent.

会议

IRF7bladder cancerproliferation

Cucurbitacin B induces DNA damage and autophagy mediated by reactive oxygen species (ROS) in breast

Cucurbitacin B (Cuc B), a tetracyclic triterpene, is an extract from cucurbitaceous plants and has been demonstrated possessing potent anti-cancer activities.

会议

Cucurbitacin BROSDNA damageAutophagyBreast Cancer

A new oridonin analogs CYD-6-28 induces cell cycle G2/M phase arrest and apoptosis in triple negativ

Oridonin, a complexent-kaurane diterpenoid isolated from the traditional Chinese herb Isodon rubescens, has been demonstrated great potential in the treatment of various human cancers due to its uniqu

会议

Oridonin analogsTriple negative breast cancerCell cycleApoptosis

The New Synthetic Antihyperlipidaemic Drug Potassium Piperate Inhibits the Proliferation of Human Ma

Piper longum L.is a well-known traditional antihyperlipidemic medicine in China, the constituents extracted from the fruit of P.longum yielded piperine (GBO) and pipernonaline.

会议

GBKhuman mammary cancercell proliferationcell cycle

XPC维持骨髓间充质干细胞自稳防止恶性转化的作用研究

肿瘤及肿瘤干细胞的发生与成体干细胞衰老、分化异常导致的恶性转化密切相关.DNA损伤应答系统是细胞维持基因组稳定的主要防御机制，近来在P53等DNA损伤应答分子的研究中发现DNA损伤应答系统在干细胞自稳中发挥多层面作用.XPC作为重要的DNA修复与细胞周期调控分子，其异常可导致多种肿瘤发生，但XPC在干细胞自稳中的角色尚未探及.

会议

间充质干细胞XPC基因组稳定性DNA损伤修复恶性转化端粒

染色质重塑蛋白BRG1在DNA双链断裂损伤修复中的作用及机制研究

DNA双链断裂(DSBs)是一种严重的DNA损伤类型.为了维持基因组的稳定性，真核生物的DNA通过与组蛋白结合进化出更为复杂紧密的染色质结构.然而这种致密的结构对于DNA的转录，复制和修复等代谢过程是一个巨大的障碍.BRG1是染色质重塑复合物SWI/SNF的核心亚基，它具有ATP水解酶活性.已有研究发现BRG1与肿瘤发生和基因组不稳定性具有重要联系.

会议

DNA双链断裂损伤修复染色质重塑BRG1同源重组修复RAD52

The intracellular fragment of dependence receptor UNC5D is an selective cofactor for E2F1-induced ap

Spontaneous regression of neuroblastoma (NB) resembles the developmentally regulated programmed cell death (PCD) of sympathetic neurons.

会议

UNC5DE2F1apoptosisneuroblastoma

Extracellular Calumenin Suppresses ERK1/2 Signaling and Cell Migration by Protecting Fibulin-1 from

Extracellular proteins are vital for cell activities, including cell migration.Calumenin is highly conserved among eukaryotes, but its functions are largely unclear.

会议

Calumenincell migrationERK-1/2signalingfibulin-1proteolysisMMP-13

Profiling of Small Noncoding RNAs in Mouse Oocyte and Early Embryos

与本文相关的学术论文