In 2011,Hanahan and Weinberg added “Deregulating Cellular Energetics” and “Avoiding Immune Destruction” to the six p......

Viruses depend on host cellular metabolism to provide the energy and biosynthetic building blocks required for their rep......

Hepatic stellate cells(HSCs)play an important role in the initiation and development of liver fibrogenesis,and abnormal ......

Hepatocellular carcinoma(HCC)is an aggressive human cancer with increasing incidence worldwide.Multiple efforts have bee......

Endothelial cells play an obligatory role in regulating local vascular tone and maintaining homeostasis in vascular biol......

After antigen stimulation,T cells preferentially increase aerobic glycolysis to meet the bioenergetic and biosynthetic d......

RAS-driven colorectal cancer relies on glucose metabolism to support uncontrolled growth.However,monotherapy with glycol......

研究pgm、fba、gap过表达对植物乳杆菌(Lactobacillus plantarum)LR-1的抗逆性、黏附和生物被膜形成的影响.结果 表明,pgm、fba基......

Tumor cells usually show abnormally high glycolysis rate to maintain the dynamic balance of energy.The growth of tumor c......

结直肠癌(CRC)是一种高度侵袭性的恶性肿瘤，在全球范围内，其发病率和死亡率分别位居第3位和第2位。近年来，免疫检查点抑制剂(ICIs)的......

Long non-coding RNAs (lncRNAs) are poorly understood in insects.In this study,we performed genome-wide analysis of lncRN......

Neurons,especially axons,are metabolically demanding and energetically vulnerable during injury.However,the exact energy......

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A great challenge in cancer diagnosis is to locally recognize the cancer cells at the molecular level with highly specif......

Gold and carbon nanostructures have received much attention because of their distinct physicochemical properties and pro......

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Osteosarcoma (OS) is the most common primary bone tumor, occurring frequently in adolescents and possessing a high malig......

Objective Background: Propofol is one of the most commonly used intravenous anesthetics,and,propofol inhibits tumor cell......

Objective Malignant solid tumors usually rely on aerobic glycolysis to generate ATP,including CRC....

Objective Gallbladder cancer(GBC)is the most highly aggressive cancer of biliary tract,but effective therapeutics are la......

Objective Esophageal cancer is the eighth most common cancer worldwide,and the sixth leading cause of cancer-related mor......

Objective Glioma cells rely on glycolysis to obtain energy and sustain their survival under microenvironmental stress in......

Objective This study aims to identify the potential major molecular targets involved in modulating nasopharyngeal carcin......

Objective Cancer cells are characterized by increased glucose uptake,increased lactate production,and decreased respirat......

Objective Dysregulation of metabolism plays an important role in the development and progression of cancers,while the un......

Objective Protein acetylation and succinylation have gradually showed their importance in cancer investigation.The simil......

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MicroRNAs(miRNAs)affect cancer cell glucose metabolism by targeting mRNAs of diverse enzymes that have been implicated i......

Cancer cells use aerobic glycolysis preferentially for energy provision, and this metabolic change is critical for tumor......

Aim Autosomal dominant polycystic kidney disease (ADPKD) affects between 1 in 400 to 1000 individuals and is characteriz......

Fas-associated death domain-containing protein (FADD),a classical apoptotic signaling adaptor,also takes part in many no......

Molecular targeted therapy has been developed for cancer chemoprevention and treatment.Cancer cells have different metab......

MicroRNA-126 (MiR126) was found to be frequently lost in many types of cancer including malignant mesothelioma (MM), whi......

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Currently,the incidence and mortality from lung cancer manifests an increasing trend.Non-small cell lung cancer (NSCLC) ......

Background: Kras activation and p16 inactivation are required for development of pancreatic ductal adenocarcinoma(PDAC).......

Objective Objectives: Esophageal squamous cell carcinoma(ESCC)occurs with high frequency in China and the prognosis is p......

Pyruvate dehydrogenase (PDH) is the multi-enzyme complex of mitochondrion.Its catalysis is of great importance in the pr......

As a thermoplastic polymer resin with excellent mechanical property and chemical stability,poly ethylene terephthalate(P......

肺脏作为气体交换的场所，新陈代谢较为活跃，其能量消耗对调节普通细胞功能及维持肺组织合成肺表面活性物质等独特功能均必不可少。肺......

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Acute liver failure(ALF)is a fatal clinical syndrome with no special drug.Recent evidence shows that modulation of macro......

Anexelekto(AXL),a member of the TYRO3-AXL-MER(TAM)family of receptor tyrosine kinases(RTK),is overexpressed in varieties......

Enhanced glycolysis is a distinct feature associated with numerous stem cells and cancer cells.However,little is known a......

Hepatocellular carcinoma(HCC)is one of the most prevalent cancers worldwide,accounting for approximately 75%-85%of prima......

有氧糖酵解是恶性肿瘤的特征之一，该能量代谢方式的改变可缩短供能周期，提高供能速率，而葡萄糖不完全氧化导致的中间产物富余又能使肿......

　　Pyruvate dehydrogenase(PDH)is the multi-enzyme complex of mitochondrion.Its catalysis is of great importance in the ......

Parental transcript legacy have important roles in fertilization and early embryo development.However, the biochemical m......