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  5. Shp2 is required for trophoblast invasion and labyrinth trophoblast progenitor cell proliferation

Shp2 is required for trophoblast invasion and labyrinth trophoblast progenitor cell proliferation

来源 :中国生理学会第24届全国会员代表大会暨生理学学术大会 | 被引量 : 0次 | 上传用户：jql
【摘 要】
：
The nonreceptor tyrosine phosphatase SHP2 (PTPN11) is a ubiquitously expressed molecule which regulates cellular proliferation,survival,migration,and differentiation during development.Homozygous of s
【作 者】
：
张爽 Shuangbo Kong Hao Ran Weiwei Wu Zhaowei Tu Zhongxian Lu Haibin Wang 
【机 构】
：
中国科学院动物研究所生殖生物学国家重点实验室,北京,100101
【出 处】
：
中国生理学会第24届全国会员代表大会暨生理学学术大会
【发表日期】
：
2014年7期
【关键词】
：
Shp2 placenta trophoblast invasion labyrinth 
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　　The nonreceptor tyrosine phosphatase SHP2 (PTPN11) is a ubiquitously expressed molecule which regulates cellular proliferation,survival,migration,and differentiation during development.Homozygous of shp2 null embryos died shortly after implantation due to failed trophoblast survival.However,the genetic role of Shp2 during placentation is still largely unknown.
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