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  5. Implications of Bit1 and AIF overexpressions in esophageal squmous cell carcinoma

Implications of Bit1 and AIF overexpressions in esophageal squmous cell carcinoma

来源 :2013医学前沿论坛暨第十三届全国肿瘤药理与化疗学术会议 | 被引量 : 0次 | 上传用户：linlinlin123456
【摘 要】
：
Overwhelming evidence has demonstrated that Bcl-2 inhibitor of transcription 1 (Bitl) and apoptosis-inducing factor (AIF) as mitochonodrial proteins are implicated in the development and progression o
【作 者】
：
Tianli Fan Fang Tian Shanyong Yi Yang Ke Shengna Han Lirong Zhang Hongtao Liu 
【机 构】
：
Department of Pharmacology,School of Basic Medicine,Zhengzhou University,100 Kexue Avenue,ZhengZhou,
【出 处】
：
2013医学前沿论坛暨第十三届全国肿瘤药理与化疗学术会议
【发表日期】
：
2013年12期
【关键词】
：
Bcl-2 inhibitor of transcription 1 apoptosis-inducing factor esophageal squamous 
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Overwhelming evidence has demonstrated that Bcl-2 inhibitor of transcription 1 (Bitl) and apoptosis-inducing factor (AIF) as mitochonodrial proteins are implicated in the development and progression of a variety of tumors.However,their expressions and biological functions in esophageal squamous cell carcinoma (ESCC) remains to be delineated.In the present study,we found that Bitl,AIF and Bcl-2 levels in ESCC tissues were significantly higher than those in normal esophageal epithelial tissues and dysplasia tissues (P＜0.05).
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