Telomerase reverse transcriptase gene from greasyback shrimp Metapenaeus ensis: isolation,genomic or

来源 :第三届全国发育生物学大会 | 被引量 : 0次 | 上传用户：nrykapnry

【摘要】

：

【作者】

：

Cuicui Liang Yuhao Wang Yujie Wang Xuemei Chen Huarong Guo

【机构】

：

Ministry of Education Key Laboratory of Marine Genetics and Breeding, College of Marine Life Science

【出处】

：

第三届全国发育生物学大会

【发表日期】

：

2016年8期

【关键词】

：

telomerase telomerase reverse transcriptase (TERT) gene shrimp Metapenaeus ensis

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Telomerase plays a crucial role in the maintenance of telomere length and chromosome stability.It consists of a catalytic subunit of telomerase reverse transcriptase (TERT),a short RNA element and one or two associated proteins.The expression level and activity of TERT are of vital importance for the proliferation,differentiation and senescence of eukaryotic cells.

其他文献

New insights into the evolutionary characteristics of missing-protein-encoding genes

Although the "missing protein" is a temporary concept in Chromosome-Centric Human Proteome Project (C-HPP)[1],the biological information for their "missing" could be an irnportant clue in evolutionary

会议

missing proteinparalogous gene groupspatial-temporal specific genes KRAB-conta

Modeling the Structure of E-pili of Geobacter sulfurreducens

Background: The electrically conductive pili (e-pili)[1]of Geobacter sulfurreducens have environmental and practical significance because of their capability of transferring electrons along the length

会议

e-piliGeobacter sulfurreducensstructure modeling

Deep network architecture for protein-protein interaction interface residue pair prediction

Motivation: Proteins usually fulfill their biological functions through interacting with other proteins.Although some methods have been developed to predict the binding sites of a monomer protein,whic

会议

deep network architectureprotein-protein interactionLSTMinterface residue pai

Protein structure alignment and the discovery of new functions

This paper introduces the principles and methods of protein structure alignment,here,taking SPalignNS algorithm and TMalign algorithm for instance,The main content of this paper is that used two algor

会议

protein structure alignmentSPalignNSTMalignfunctional prediction

Unraveling low-resolution structural data of large biomolecules by constructing atomic models with e

Various low-resolution experimental techniques have gained more and more popularity in obtaining structural information of large biomolecules.In order to interpret the low-resolution structural data p

会议

Structural biologySmall-angle X-ray scattering (SAXS)Electron microscopy (EM)

FKBP51在抵制高脂诱导肥胖中的作用

[目的]FKBP51是一种具有肽基脯氨酰顺-反异构酶(PPIase)活性的免疫亲和蛋白,它含有多肽重复序列结构域(TPR),能够介导蛋白与蛋白之间的相互作用。已有研究表明,FKBP51在脂肪生成中发挥重要的作用。因此,我们通过对FKBP51基因敲除小鼠表型的分析,来探究FKBP51的缺失与肥胖的关系。

会议

FKBP51基因敲除小鼠能量代谢肝脏病理学

免疫亲合蛋白FKBP51通过TGF-β1/Smads通路参与CCl4诱导的小鼠肝脏纤维化

[背景与目的]肝纤维化是各种慢性肝病向肝硬化、肝癌发展的必经阶段。虽然肝纤维化发病率高，但对其发病机制尚不完全清楚，且无有效的抗纤维化治疗手段。本研究通过创建CCl4诱导的小鼠肝脏纤维化模型，研究FKBP51在肝脏纤维化中的作用，以期研究肝脏纤维化的发生机理，并为寻找预防和治疗肝脏纤维化提供新的靶点。

会议

FKBP51肝脏纤维化TGF-β1/Smads信号通路

miR-424-5p在肺癌细胞A549中的表达及作用研究

MicroRNA (miRNA)是一类小的非编码RNA,主要通过与靶基因mRNA的3非翻译区配对来降解靶基因mRNA或抑制其表达,从而实现在转录后水平调控靶基因的表达.研究表明miRNA与人类多种肿瘤的调节密切相关.本研究检测了miR-424-5p在肺癌细胞A549中的表达及对肿瘤细胞恶性表型的作用.首先利用Real-time PCR检测表明miR-424-5p在肺癌细胞系A549中的表达高于H4

会议

miR-424-5p肺癌A549

Mutations of PQBP1 in Renpenning syndrome gain the function of promoting ubiquitin-mediated degradat

Renpenning syndrome is a group of X-linked intellectual disability (XLID) syndromes caused by mutations in human polyglutamine-binding protein 1 (PQBP1) gene.

会议

X-linked intellectual disabilitysynaptic functionprotein degradationPQBP1FMR

Glutathione peroxidase 4 inhibits Wnt/β-catenin signaling and regulates dorsal organizer formation i

The Wnt/β-catenin signaling pathway plays pivotal roles in axis formation during embryogenesis and in adult tissue homeostasis.Glutathione peroxidase 4 (GPx4) is a selenoenzyme and participates in per

会议

glutathione peroxidase 4Wnt/β-catenin signalingTcf/Lefzebrafishdorsal organi

Telomerase reverse transcriptase gene from greasyback shrimp Metapenaeus ensis: isolation,genomic or

与本文相关的学术论文