telomerase相关论文
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Expression of telomerase activity, telomerase RNA component and telomerase catalytic subunit gene in
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Potent antitumoral effects of a novel gene-viral therapeutic system CNHK300-mEndostatin in hepatocel
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Objective: To investigate the influence of anti-keratin autoantibodies (AK auto Abs) on telomerase activity of squamous ......
目的 探讨澳洲茄胺盐酸盐(SBHL)在三氧化二砷(As2O3)诱导的HeLa细胞凋亡中的作用及对细胞端粒酶活性的影响.方法 采用细胞培养的方......
目的评估液基细胞学检验(TCT)、人乳头状瘤病毒(HPV)、c-MYC、人染色体端粒酶RNA基因(hTERC)联合检测在宫颈癌筛查中的应用价值。......
目的 观察大蒜素联合TFP(紫杉醇+5-氟尿嘧啶+顺铂)方案治疗晚期胃癌患者的疗效和不良反应发生情况，以及对端粒酶活性的影响。方法采......
目的：探讨松针油对人乳腺癌细胞（MCF7）影响及可能损伤、凋亡及自噬的机制。方法：用不同浓度的松针油处理MCF7细胞24、48及72h后观察，用......
目的观察端粒酶基因在乳腺癌前病变-乳腺导管非典型增生及乳腺癌中的表达,探讨其与恶性转化的关系.方法应用原位杂交方法评价端粒......
目的为探讨抑制人端粒酶的模板RNA成分(hTR)能否抑制人胰腺癌细胞的端粒酶活性及细胞生长能力.方法用分子克隆方法将593 bp 的hTR......
目的 观察抑制性神经递质γ-氨基丁酸(GABA)对人胆管癌细胞株QBC939生物学行为的影响.方法 采用MTF比色法观察GABA对人系胆管癌细......
目的探讨尿液中端粒酶活性在尿路上皮癌的诊断和监测复发中的意义.方法采用PCR-ELISA法对54例尿路上皮癌尿液中端粒酶活性进行了检......
Objective: To investigate the effect of moxibustion on telomerase activity and genes expression in tissues of senescent ......
Diagnosis of pancreatic cancer by cytology and telomerase activity in exfoliated cells obtained by p
BACKGROUND:Telomerase activity is reported to be speciifc and frequent in human pancreatic cancer. We conducted this stu......
survivin是近年发现的一种凋亡抑制基因,具有抑制细胞凋亡的作用[1],人端粒酶逆转录酶(hTERT)是端粒酶(telomerase)活性的限制性组......
近年研究表明,粪便中肿瘤相关基因的检测有助于结直肠癌的早期诊断.端粒酶逆转录酶(humantelomerase reverse transcriptase,hTERT......
大多数恶性肿瘤细胞包括结直肠癌细胞的端粒酶活性明显高于正常,并且研究发现人端粒酶组成成分之一人端粒酶逆转录酶能够间接反应......
Hepatocellular carcinoma(HCC)is one of the mostfrequent malignant tumors and is the second mostcommon cause of cancer d......
Geron等通过遗传工程使细胞表达端粒酶(telomerase),延长了正常人的包皮纤维母细胞及视网膜色素上皮细胞的寿命。端粒酶是保护染......
端粒酶(telomerase)与细胞恶变、肿瘤的发生发展密切相关[1].而端粒酶催化亚单位(hTERT)可能在端粒酶活性调节中起重要作用[2]。......
,TGF-beta receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senesc
Human telomerase reverse transcriptase (hTERT) plays a central role in telomere lengthening for continuous cell prolifer......
Pluripotent stem cells (PSCs) such as embryonic stem cells (ESCs),ESCs derlved by somatic cell nuclear transfer (ntESCs)......
目的研究组蛋白去乙酰化酶抑制剂曲古菌素A(trichostatin A,TSA)抑制HL-60细胞端粒酶活性及亚单位hTERT的表达并诱导凋亡的机制.方......
Fibroblast growth factor receptor 3 effects on proliferation and telomerase activity in sheep growth
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
目的 探讨端粒酶与bcl-2在宫颈癌中的表达及其相关性,为宫颈癌的早期诊断、治疗和预后判断提供一定的理论基础.方法 采用免疫组织......
Relationship between the Expression of Telomerase and Human Papillomavirus Infection in Invasive Ute
Telomerase activity was examined in invasive cervical carcinoma to assess whether it is activated during cervical malign......
目的构建由人端粒酶逆转录酶(hTERT)启动子调控的NIS基因以及由早期生长应答因子1(Egr1)启动子调控的人纤溶酶原Kringle 5(K5)基因......
甲状腺乳头状癌(PTC)是甲状腺癌最常见的病理类型，其发病率在全球范围内迅速增长。V-raf鼠肉瘤滤过性病毒致癌同源体B1基因(BRAF)V6......
目的探讨端粒酶调控因子PinX1对肝癌细胞增殖和侵袭能力的影响。方法构建稳定表达PinX1的肝癌细胞PinX1-7721（实验组）及其对照细胞VE......
HumantelomeraseRNA (hTR) playsanimportantroleindeterminingrepeatedtelomeresequenceandtheexpressionofanantisensetelomeras......
Background It was reported that telomerase expression is closely associated with cellular immortality and cancer. This s......
Experimental study on anti-neoplastic activity of epigallocatechin-3-gallate to digestive tract carc
Background Epigallocatechin-3-gallate (EGCG) has been demonstrated to have anti-neoplastic activity, but the effective c......
Potent antitumoral effects of a novel gene-viral therapeutic system CNHK300-mEndostatin in hepatocel
Background The expression of therapeutic gene and its anti-tumor effects will be augmented and a synergism of oncolytic ......
Inhibition of the proliferation of human gastric cancer cells SGC-7901 in vitro and in vivo using Bc
Background Bcl-2,the anti-apoptotic protein is overexpressed in the majority of gastric cancers and associated with its ......
Inhibition of telomerase with human telomerase reverse transcriptase antisense enhances tumor necros
Background Telomerase activity is found in 85%-90% of all human cancers but not in their adjacent normal cells.Human tel......
Attenuation of Telomerase Activity by siRNA Targeted Telomerase RNA Leads to Apoptosis and Inhibitio
OBJECTIVE Telomerase is an attractive molecular target for cancer therapy because the activation of telomerase is one of......
Identification of the Tumor Factor of Abnormal Cancer Methylation Enzymes as the Catalytic Subunit o
OBJECTIVE The objective was to study the relationship between the tumor factor of cancer MATLT and the catalytic subunit......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
