Light and pH dual responsive polyion complex micelles for efficient protein delivery

来源 :The Third Symposium on Innovative Polymers for Controlled De | 被引量 : 0次 | 上传用户:liongliong521
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  Since the development of the first protein drug (human insulin) more than 30 years ago,protein and peptide-based therapeutics have attracted widespread attention for effective treatment of human diseases [1].To better protect proteins during circulation,protein carriers are especially important for intracellular protein delivery.Polyion complex micelles are especially promising since the complexes from cationic polymer and anionic protein can maintain a stable state through electrostatic interactions [2].
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