【摘 要】
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Persistent organic pollutants(POPs)are one class of environment pollutants that proved to be harmful to the environment and human health.They are causing ever-increasing concerns from scientists,the p
【机 构】
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Department of Chemistry and the MOE Key Laboratory of Spectrochemical Analysis & Instrumentation,Xia
【出 处】
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2016年分析化学前沿国际研讨会及中美分析化学研讨会
论文部分内容阅读
Persistent organic pollutants(POPs)are one class of environment pollutants that proved to be harmful to the environment and human health.They are causing ever-increasing concerns from scientists,the public and the government.Researches about the distribution and metabolism of POPs are significant for us to make a better understanding of how to protect our environment and health.These years we established a spatiotemporal monitoring technique of atmospheric halogenic POPs(H-POPs)using tree barks and bark pockets as green passive sampling media [1-4] based on a pulsed large volume injection capillary gas chromatography coupled with electron-capture negative ionization quadrupole mass spectrometric(pLVI-cGC/ECEI-qMS)method [5],and applied them to monitoring atmospheric H-POPs distribution across Mainland China and to uncover the historical evolution of atmospheric H-POPs from 1873 to 2005 in southeastern China.Furthermore,the metabolism pathways of H-POPs as exemplified by 2,2′,4,4′-tetra-bromodiphenyl ether(BDE-47)in the microsomes was investigated using a pentafluorobenzoyl-derivatization cGC/ECNI-qMS [6].We found two novel metabolites,dihydroxylated 3,6-di-OH-BDE-47 and dihydroxylated 3,5-di-OH-tetrabrominated dioxin,in addition to the already known metabolites of BDE-47.This methodological development and its subsequent findings of the metabolic pathways of BDE-47 provided experimental evidence for understanding its dioxin-like behavior and endocrine disrupting risk.
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