In this talk,it will be shown that based on the membrane emulsion technique and the fluid flowing in a microchannel,a membrane dispersion microreactor was proposed,this reactor can significantly improve the mixing efficiency through the CFD simulation.This microreactor were used to prepare the nanoparticles such as CaCO3,SiO2 and ZnO nanoparticles through the precipitation method,the average diameter of nanoparticles can be controlled from 20nm to 100nm by adjusting the membrane pore size,flow rate and the concentration of raw materials,through scaling up the microreactor,the preparation of CaCO3 nanoparticles has reached a commercial scale; more recently,the microreactor was used to realize the hydration of acrylonitrile to produce acrylamide,it was found that in this reactor,the acrylonitrile was dispersed into the continuous phase(the aqueous phase contains nitrile hydratase(NHase)as droplets with a diameter ranged from 25 to 35 μm,hence the mass transfer specific surface area was significantly increased,and the concentration of acrylamide reached 52.5 wt%within 50 min.By contrast,in stirred tanks,the concentration of acrylamide only got 39.5 wt%within 245 min.