Recent experiments have pointed out the cellular uptake is strongly dependent on the physical dimensions of endocytosed nanoparticles,showing that the optimal radius of endocytosed bioparticle is abou
Single stranded guanine-rich sequences fold into compact G-quadruplexes.Although G-triplexes have been proposed and demonstrated as intermediates in the folding of G-quadruplexes,there is still a deba
Localized surface plasmon resonance(LSPR)phenomenon refers to a coherent oscillation of electrons taking place on the surface of noble metal nanoparticles(mainly Au and Ag)in response to an alternatin
Force is increasingly recognized as an important element in controlling biological processes.Forces are able to deform native protein conformations leading to protein-specific effects.
Filamin A 是细胞微丝骨架的交联蛋白,还可以连接细胞微丝骨架到细胞膜.Filamin A 包含氨基端的微丝结合结构域和24 个免疫球蛋白的结构域.24 个免疫球蛋白可以分为三段,第一段包含1-15 号结构域,构成一个线性的杆状结构;第二段包含16-23 号结构域,但是构成相对紧凑的结构;第三段是可以结合成二居聚的24 号结构域.