Optogenetic activation of medial septal cholinergic neurons during slow-wave sleep disrupts hippocam

来源 :长三角地区神经科学论坛2016暨第八次会员代表大会 | 被引量 : 0次 | 上传用户：opou

【摘要】

：

　　Existing pharmacological and lesion data indicate that acetylcholine(ACh)plays a crucial role in memory acquisition and consolidation.Elevated ACh release f

【作者】

：

林龙年

【机构】

：

华东师范大学"脑功能基因组学"教育部重点实验室

【出处】

：

长三角地区神经科学论坛2016暨第八次会员代表大会

【发表日期】

：

2016年9期

【关键词】

：

medial septum acetylcholine hippocampus memory consolidation ripple oscillations

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论文部分内容阅读

　　Existing pharmacological and lesion data indicate that acetylcholine(ACh)plays a crucial role in memory acquisition and consolidation.Elevated ACh release from the cholinergic basal forebrain enhances memory acquisition during waking,while low levels of ACh mediates memory consolidation during slow-wave sleep(SWS).

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Optogenetic activation of medial septal cholinergic neurons during slow-wave sleep disrupts hippocam

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