ORF59 COOPERATES WITH ORF40 IN DISTORTING THE AT-RICH PALINDROME REGION OF MURINE GAMMAHERPESVIRUS 6

来源 :17th International Workshop on Kaposi’s Sarcoma Associated H | 被引量 : 0次 | 上传用户：anjo888

【摘要】

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Lytic replication is essential to virus spread and plays important roles in tumorigenesis caused by gammaherpesviruses.Murine gammaherpesvirus-68 (MHV-68) is ge

【作者】

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Chuanhui Han Hongtao Xu Liang He Danyang Gong Jing Qi Hongyu Deng

【机构】

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CASKeyLaboratoryofInfectionandImmunity,InstituteofBiophysics,ChineseAcademyofSciences,Beijing100101,

【出处】

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17th International Workshop on Kaposi’s Sarcoma Associated H

【发表日期】

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2014年7期

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Lytic replication is essential to virus spread and plays important roles in tumorigenesis caused by gammaherpesviruses.Murine gammaherpesvirus-68 (MHV-68) is genetically related to Kaposis sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV) and replicates robustly in vitro, providing an efficient model for studying the lytic genome replication of gammaherpesviruses during de novo infection.We have previously identified two copies of origin of lytic replication (oriLyt), located towards the left and right genomic termini of MHV-68, respectively.

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ORF59 COOPERATES WITH ORF40 IN DISTORTING THE AT-RICH PALINDROME REGION OF MURINE GAMMAHERPESVIRUS 6

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