A RHESUS RHADINOVIRUS VIRAL INTERFERON REGULATORY FACTOR IS VIRIONASSOCIATED AND INHIBITS THE EARLY

来源 :17th International Workshop on Kaposi’s Sarcoma Associated H | 被引量 : 0次 | 上传用户：robinleslie

【摘要】

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The interferon (IFN) response is the earliest host immune response dedicated to combating viral infection.Because of this, many viruses have evolved strategies

【作者】

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Gabriela Morin Scott Wong

【机构】

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VaccineandGeneTherapyInstitute,OregonHealth&ScienceUniversity,Beaverton,USA

【出处】

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17th International Workshop on Kaposi’s Sarcoma Associated H

【发表日期】

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2014年7期

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The interferon (IFN) response is the earliest host immune response dedicated to combating viral infection.Because of this, many viruses have evolved strategies to subvert this potent antiviral response.Two closely related gammaherpesviruses, Kaposis sarcoma-associated herpesvirus (KSHV) and rhesus rhadinovirus (RRV), are unique in that they express viral homologues to cellular interferon regulatory factors (IRFs), deemed viral IRFs (vIRFs).

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A RHESUS RHADINOVIRUS VIRAL INTERFERON REGULATORY FACTOR IS VIRIONASSOCIATED AND INHIBITS THE EARLY

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