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  5. Synergic Effects of Paclitaxel and Temozolomide co-loaded in mPEG-PLGA Nanoparticles Attenuate Gliob

Synergic Effects of Paclitaxel and Temozolomide co-loaded in mPEG-PLGA Nanoparticles Attenuate Gliob

来源 :2014年中国药物制剂大会——中国药学会药剂专业委员会年会、第六届亚洲阿登制药技术研讨会暨国际控释协会中国分会年会 | 被引量 : 0次 | 上传用户：yu_threestone
【摘 要】
：
Purpose: This work was conducted to determine the optimal synergic weight ratios of Paclitaxel (PTX) and Temozobmide (TMZ), and further developed a dual drug-loaded delivery system based on mPEG-PLGA
【作 者】
：
Yuanyuan Xu Ming Shen Ying Sun Yanwei Teng Yourong Duan 
【机 构】
：
State Key Laboratory of Oncogenes and Related Genes,Shanghai Cancer Institute,Renji Hospital,School
【出 处】
：
2014年中国药物制剂大会——中国药学会药剂专业委员会年会、第六届亚洲阿登制药技术研讨会暨国际控释协会中国分会年会
【发表日期】
：
2014年8期
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Purpose: This work was conducted to determine the optimal synergic weight ratios of Paclitaxel (PTX) and Temozobmide (TMZ), and further developed a dual drug-loaded delivery system based on mPEG-PLGA nanoparticles (PTX/TMZ-NPs) by a double emulsion solvent evaporation method creatively, aiming to improve these two drugs chemotherapy efficacy for glioblastoma.
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