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  5. MiR-30c contributes to the development of hypoxia pulmonary hypertension through PDGFR

MiR-30c contributes to the development of hypoxia pulmonary hypertension through PDGFR

来源 :中国生理学会第24届全国会员代表大会暨生理学学术大会 | 被引量 : 0次 | 上传用户：pootcat
【摘 要】
：
Pulmonary arterial hypertension (PAH) is characterized by enhanced proliferation and reduced apoptosis of pulmonary artery smooth muscle cells (PASMCs).MicroRNAs have been implicated in the regulation
【作 者】
：
郑晓东 邢妍 朱大岭 
【机 构】
：
哈尔滨医科大学大庆校区基础医学院,大庆 163319 哈尔滨医科大学大庆校区药学院;黑龙江省省部共
【出 处】
：
中国生理学会第24届全国会员代表大会暨生理学学术大会
【发表日期】
：
2014年7期
【关键词】
：
hypoxic pulmonary hypertension mircroRNA 30c pulmonary artery smooth muscle cell 
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　　Pulmonary arterial hypertension (PAH) is characterized by enhanced proliferation and reduced apoptosis of pulmonary artery smooth muscle cells (PASMCs).MicroRNAs have been implicated in the regulation of cell proliferation and might be implicated in the etiology of PAH.Here we show that hypoxia inhibits miR-30c expression in PASMCs.
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