• 不 限
  • 期刊论文
  • 硕博论文
  • 会议论文
  • 报 纸
  • 英文论文
  2. 您的位置
  3. 首页
  4. 会议论文
  5. Surface charge triggered intestinal epithelial tight junction opening based on chitosan nanoparticle

Surface charge triggered intestinal epithelial tight junction opening based on chitosan nanoparticle

来源 :Fourth Symposium on Innovative Polymers for Controlled Deliv | 被引量 : 0次 | 上传用户：anonyjim
【摘 要】
：
Exogenous insulin is essential in treating diabetes mellitus,Normally exogenous insulin was first transported to the liver via the portal circulation,resulting in a hypoglycemic effect.Oral delivery o
【作 者】
：
Juan Wang Ming Kong 
【机 构】
：
College of Marine Life Science,Ocean University of China,Qingdao 266003,China
【出 处】
：
Fourth Symposium on Innovative Polymers for Controlled Deliv
【发表日期】
：
2016年11期
【关键词】
：
tight junction oral insulin delivery surface charge CMCS CS nanoparticles 
下载到本地 , 更方便阅读
下载此文 赞助VIP
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
　　Exogenous insulin is essential in treating diabetes mellitus,Normally exogenous insulin was first transported to the liver via the portal circulation,resulting in a hypoglycemic effect.Oral delivery of exogenous insulin is a preferred route owing to its ability to reproduce the physiological profile of insulin undergoing the first hepatic bypass.
其他文献
An agarose-PEI-HA copolymer as tumor-targeted gene vector with high efficiency and low toxicity
Development of effective gene vectors is critical to the success of gene therapy[1].Up-to-date,readily-available gene vectors are limited due to their inefficiency,cytotoxicity and poor targeting capa
会议
gene deliverygene expressionpolyethyleneiminetumor targeting
Enhanced anti-tumor efficacy by co-delivery of GDC-0449 with size-tunable polymeric SN38 nanoparticl
Pancreatic ductal adenocarcinoma (PDAC) is the most lethal human cancer with a poor prognosis and a 5-year survival rate of less than 7%.In recent years,the roles of fibroblasts in PDAC microenvironme
会议
pancreatic cancerpancreatic stellate cellsGDC-0449SN-38size-tunable nanopart
Highly water-soluble,stable,and biocompatible PAMAM dendrimers entrapped gold nanoparticles for cata
Dendrimer entrapped metal nanoparticles (M-DENs) are widely studied for their potential applications in catalysis,drug delivery,photophysics,diagnosis and sensing.The high level of control over the ar
会议
dendrimerszwitterionicgoldnanoparticlesbiocompatible
Engineering starch-based capsules for controlled delivery
The medicinal capsules offer better solid dosage form for drugs with low compressibility,slow dissolution and bitter tasting,and require disintegration in stomach as rapid as possible in the most case
会议
starchcapsulecontrolled deliverymodification
Porous nitrogen-doped biochar derived from chitosan for absorption of creatinine
Creatinine is a typical low molecular uremic toxin which accumulates in the bodies of chronic renal failure (CRF) patients and then produces toxic effect[l].The clearance of creatinine is of great imp
会议
porousnitrogen-dopedbiocharabsorptioncreatineine
Polymer donors of nitric oxide for enhanced accumulation of anticancer agents in solid tumors
Although current cancer therapy enables complete cure for a certain percentage of patients,there are still many obstacles that have to be overcome in order to further improve the overall outcome.
会议
EPR effectsolid tumorHPMA copolymerdrug delivery
Controlled thermo-triggered drug release system based on propionylated amylose helix nanoclusters
Thermo-triggered drug release systems are widely used as drug carriers.Nevertheless,complicated carrier materials are required and their temperature response ranges are difficult to control[1].
会议
thermo-triggereddrug deliverypropionylated amylosehelix
Dual controlled delivery of squalenoyl-gemcitabine and paclitaxel using thermo-responsive polymeric
Gemcitabine (GEM) is the most potent anti-cancer drug for the treatment of pancreatic cancer.However,it undergoes rapid deamination in the bloodstream and becomes biologically inactive.
会议
thermo-responsivepolymeric micellessqualenoyl-gemcitabinepaclitaxelcellular
Unimer polyion complex self-assembled nanomicelle for systemic delivery of siRNA into solid tumor
For successful RNAi-based cancer therapy,a safe and efficient siRNA delivery system is needed[1].Here,we report a novel approach for preparation of a stable nanomicelle derived from unimer polyion com
会议
siRNA deliverythermosensitive polymerunimer polyion complexnanomicelle
In vivo chemo/photothermal therapy using near-infrared light triggered switchable nanoparticles agai
Bladder carcinoma is one of the most common malignancies of the genitourinary system.By taking advantages of enhanced permeation and retention (EPR) effect,the nanocarriers preferentially deliver the
会议
near-infraredEPR effectstimuli-responsivedrug delivery