The Function and Significance of SELENBP1 Downregulation in Human Bronchial Epithelial Carcinogenic

来源 :第八届中国蛋白质组学大会 | 被引量 : 0次 | 上传用户：zmh700929

【摘要】

：

To discover novel proteins associated with human lung squamous cell cancer (LSCC) carcinogenesis,iTRAQ-tagging combined with 2D LC-MS/MS analysis was used to id

【作者】

：

Gu-Qing Zeng Hong Yi Peng-Fei Zhang Rong Hu Mao-Yu Li Cui Li Zhi-Qiang Xiao

【机构】

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KeyLaboratoryofCancerProteomicsofChineseMinistryofHealth,XiangyaHospital,CentralSouthUniversity,Chan

【出处】

：

第八届中国蛋白质组学大会

【发表日期】

：

2013年9期

【关键词】

：

selenium-binding protein 1 human bronchial epithelial carcinogenesis lung squamo

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To discover novel proteins associated with human lung squamous cell cancer (LSCC) carcinogenesis,iTRAQ-tagging combined with 2D LC-MS/MS analysis was used to identify differentially expressed proteins in human bronchial epithelial carcinogenic process using laser capture microdissection-purified tissue samples.As a result,102 differentially expressed proteins were identified,and selenium-binding protein 1 (SELENBP1) was found being progressively decreased in the bronchial epithelial carcinogenic process.

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