Hydroxyapatite nano-rods/fibers patterned oxides-based coatings were fabricated on titanium,zirconium,tantalum and magnesium,respectively,using a hybrid approach of microarc oxidation and hydrothermal treatment.They could adhere firmly to the underlying metallic materials and retain long-term bonging strength stability.The regulating roles of topographical parameters of the patterned coatings in the behavior of cells(such as osteoblast and bone mesenchymal stem cell)and bone formation were herein demonstrated.