表达猪2型圆环病毒Cap蛋白重组支气管败血波氏杆菌作为猪圆环病毒候选疫苗的初步研究

来源 :2013国际猪繁殖与呼吸综合征学术研讨会 | 被引量 : 0次 | 上传用户：leezuo

【摘要】

：

目的将猪2型圆环病毒(PCV2) ORF2基因重组支气管败血波氏杆菌(Bb),获得能表达猪2型圆环病毒Cap蛋白的减毒支气管败血波氏杆菌,针对猪2型圆环病毒引起的猪多系统功能障碍性疾病,开发一种新型疫苗,利用Bb能在猪呼吸道黏膜上皮细胞有效和有限地定殖并激发黏膜免疫的能力,将PCV2的免疫原性蛋白通过呼吸道途径进行免疫,从而达到预防PCV2的感染,为该重组菌株作为候选疫苗提供科学依据.

【作者】

：

寿琎夏欣樊翠华吴斌

【机构】

：

华中农业大学农业微生物国家重点实验室,湖北武汉430070

【出处】

：

2013国际猪繁殖与呼吸综合征学术研讨会

【发表日期】

：

2013年12期

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表达猪2型圆环病毒Cap蛋白重组支气管败血波氏杆菌作为猪圆环病毒候选疫苗的初步研究

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