【摘 要】
：
CD147 is highly expressed in tumor tissues and on the membrane of tumor cells.Our previous studies have proved that the interaction of CD147 with integrin can activate the downstream signaling pathway
【机 构】
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Cell Engineering Research Center and Department of Cell Biology, State Key Laboratory of Cancer Biol
【出 处】
：
中国细胞生物学学会2015年全国学术大会
论文部分内容阅读
CD147 is highly expressed in tumor tissues and on the membrane of tumor cells.Our previous studies have proved that the interaction of CD147 with integrin can activate the downstream signaling pathway of PI3K-Akt, which increases matrix metalloproteinase (MMPs) secretion of tumor cells, thereby promoting rumor cell invasion and metastasis.
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