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Background Coronary artery chronic occlusion (CTO) lesions are usually the coronary occlusion pathological changes beyond 3 months; incidence of coronary heart disease is about 20％-40％.CTO lesions successful percutaneous coronary intervention (PCI) can effectively relieve clinical angina symptoms improve left ventricular function, reduce or avoid the proportion of CABG and potential benefits, improve forward survival rate.However, the PCI success rate for CTO lesions is 65％-92％.Previous reports that the femoral-radial artery access for PCI in CTO patients is not really solve the problem in patients with vessel related complications and bed of discomfort.This study will compare the clinic feasibility and safety on brachial-radial (TB-RI) vs.femoral-radial (TF-RI) artery access for percutaneous coronary intervention in patients with chronic total coronary occlusion disease.