论文部分内容阅读
Methylene blue(MB)was first synthesized in 1876 and has been used as treatment for malaria,methemoglobinemia,and cyanide poisoning.
Methylene Blue improves the disruption of blood brain barrier and attenuates astroglia activation af
【摘 要】
：
Methylene blue(MB)was first synthesized in 1876 and has been used as treatment for malaria,methemoglobinemia,and cyanide poisoning.
【机 构】
：
Department of Pathophysiology,Beijing Neurosurgical Institute,Capital Medical University,Beijing,100
【出 处】
：
The 6th FAONS Congress and 11th Biennial Conference of CNS(第
【发表日期】
：
2015年3期
其他文献
To define the factors responsible for ischemia-induced blood-brain barrier damage is first necessary before a new strategy can be developed to counter the adverse effect of ischemia-induced endothelia
Preconditioning with recombinant HMGB1 induces ischemic tolerance in a rat model of focal cerebral i
Preconditioning means that a previous minor insult prepares the body to better withstand a subsequent larger insult.High mobility group box 1(HMGB1)is a reported that mediates High mobility group box
Luoyutong capsule protects against cerebral ischemia-reperfusion injury in rats involving neural pla
Previous study observed that Luoyutong(LYT)capsule has a definite curative effect in patients with stroke.However,nothing has been known about the underlying mechanism of LYT in protecting cerebral is
Histidine provides long-term neuroprotection after cerebral ischemia through promoting astrocyte mig
Objective The formation of glial scar impedes the neurogenesis and neural functional recovery following cerebral ischemia.Histamine showed neuroprotection at early stage after cerebral ischemia,howeve
Objective Neuroinflammation after cerebral ischemia/reperfusion(I/R)is characterized by the accumulation of inflammatory cells and mediators in brain.
Pharmacological inhibition of HDAC6 alleviates brain infarction and functional deficits after experi
Objective Histone deacetylase(HDAC)6 exists exclusively in the cytoplasm and deacetylates cytoplasmic proteins such as α-tubulin.
Methylene blue(MB)was mainly used in the clinical treatment of cyanide poisoning and methemoglobinemia.Currently,the neuroprotective effect of MB has been identified against various brain disorders,in
Cerebral ischemia-induced occludin degradation promotes blood brain barrier endothelial cell apoptos
Intracerebral hemorrhage is the most dangerous complication in tPA thrombolytic therapy for ischemic stroke,which occurs as a consequence of endothelial cell apoptosis of the blood brain barrier(BBB)d
Role of autophagy in the cerebral ischemic reperfusion injury of mice and its cPKCγ-mediated molecul
To investigate the progression of autophage in the peri-infarct tissue after middle cerebral artery occlusion(MCAO)mice models; To explore the function of autophage and its possible molecular mechanis