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  5. Ethanol modulates the spontaneous complex spike signaling of cerebellar Purkinje cell in vivo in mic

Ethanol modulates the spontaneous complex spike signaling of cerebellar Purkinje cell in vivo in mic

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户：tlljs
【摘 要】
：
Cerebellar Purkinje cells(PCs)are sensitive to ethanol,which express a change in simple spike firing rate under in vitro conditions,but the effect of ethanol on spontaneous complex spike(CS)activity o
【作 者】
：
Xin-Yuan Zhang Bin-Bin Zhang De-Lai Qiu 
【机 构】
：
Cellular Function Research Center,Yanbian University,Yanji City,Jilin Province,China;Department of P
【出 处】
：
2016年国际生理学学术大会
【发表日期】
：
2016年6期
【关键词】
：
Cerebellar Purkinje cell complex spike CB1 receptor in vivo patch-clamp recordin 
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　　Cerebellar Purkinje cells(PCs)are sensitive to ethanol,which express a change in simple spike firing rate under in vitro conditions,but the effect of ethanol on spontaneous complex spike(CS)activity of PCs in living animals are currently unknown.In this study,we investigated the effect of ethanol on spontaneous CS activity of PCs in urethane-anesthetized mice,by in vivo patch-clamp recording and pharmacological methods.
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