Low-density lipoprotein-coupled micelles with reduction and pH dual sensitivity for intelligent co-d

来源 :2016年中国药物制剂大会、中国药学会药剂专业委员会2016年学术年会、中国化学制药工业协会固体制剂专业委员会2016年 | 被引量 : 0次 | 上传用户:bood
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  Objective: The existence of multidrug resistance(MDR)is a major obstacle for the clinical therapy of malignant human cancers,and the discovery of RNA interference(RNAi)provide a quite efficient gene silencing within tumor cells for reversing MDR.
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novel biomimetic drug delivery system(BDDS)inspired by the pH-dependent ferric ion-transport and release manner of transferrin(Tf)was developed for combating multidrug-resistant breast cancer.Tf-inspi
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OBJECTIVE To prepare the ibuprofen sustained-release dropping pill and evaluate its accumulative release percentage in vitro.And study the state of drug in substrate.
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