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5. Minocycline reduces neuroinflammation but does not ameliorate neuron loss in a mouse model of neurod

Minocycline reduces neuroinflammation but does not ameliorate neuron loss in a mouse model of neurod

来源 :The 6th FAONS Congress and 11th Biennial Conference of CNS(第 | 被引量 : 0次 | 上传用户：lizhuyundao

【摘 要】

：

Minocycline is a broad-spectrum tetracycline antibiotic.A number of preclinical studies have shown that minocycline exhibits neuroprotective effects in various animal models of neurological diseases.H

【作 者】

：

Shanshan Cheng Jinxing Hou Chen Zhang Congyu Xu Long Wang Xiaoxia Zou Huahong Yu Yun Shi Zhenyu Yin Guiquan Chen 

【机 构】

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Model Animal Research Center,MOE Key Laboratory of Model Animal for Disease Study,Nanjing University

【出 处】

：

The 6th FAONS Congress and 11th Biennial Conference of CNS(第

【发表日期】

：

2015年3期

【关键词】

：

neuroinflammation neurodegeneration minocycline Dicer 

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　　Minocycline is a broad-spectrum tetracycline antibiotic.A number of preclinical studies have shown that minocycline exhibits neuroprotective effects in various animal models of neurological diseases.However,it remained unknown whether minocycline is effective to prevent neuron loss.

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