论文部分内容阅读
Back ground:-By 2010, 60 % of total world burden of CAD will be born by India and this will be 4 times of Chinese & Europeans, particularly in younger population (<40 yrs) in whom it may approach 10 fold increase.Conventional risk factors play a lesser role in young whereas socioeconomic & demographic factors and infection play a significant role.Our work in recent past on CAD in young subjects is reviewed.1∶40 records (out of 739) of angiographically proved CAD were studied in 1987.All patients were male, 80% in 35-40 yr group, 57% presented with pain, 45 % with anteriorwall MI, 53%, were smokers and 48% had single vessel disease.2∶208 patients were prospectively studied in 2002 and again males predominated(90 %), more prevalent in urban areas (54%), with lesser education (71%) and low income groups (62%).Smoking (55%) and alcohol consumption (54 %) were major risk factors.Drivers (23%) and businessmen (25%) were more prone to CAD & non vegetarians were majority (93%).3: In 2003 a prospective comparative study of CAD in young patients(50 pts and 50 controls) was undertaken.Males predominated (86%).Business (26%) & smoking (64%) & Alcohol consumption (64%) were major risk factors compared to controls (8%, 26% & 30 % respectively).Diabetes, Obesity and Triglycerides were significantly more in patients than controls (26%, 48%, & 163 mg v/s 6%,14 % and 123 mg).It is evident that:-CAD in young is increasing, males predominate, more common with urban dwelling, lesser education, low in come and stressful jobs.Family H/o CAD & smoking were major risk factors.Paradoxically alcohol is more associated with CAD in young.Usual presentation is MI and single vessel disease with less post MI complications & and good prognosis.