LincSNP: a database of linking disease-associated SNPs to human large intergenic non-coding RNAs

来源 :第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会 | 被引量 : 0次 | 上传用户:qiushuigediao
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  Background: Genome-wide association studies (GWAS) have successfully identified a large number of single nucleotide polymorphisms (SNPs) that are associated with a wide range of human diseases.However, many of these disease-associated SNPs are located in non-coding regions and have remained largely unexplained.Recent findings indicate that disease-associated SNPs in human large intergenic non-coding RNA (lincRNA) may lead to susceptibility to diseases through their effects on lincRNA expression.There is, therefore, a need to specifically record these SNPs and annotate them as potential candidates for disease.
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