Quantitative Proteomics Profiling Unravels Synergetic Neuroprotective Effect of Novel Combination of

来源 :第十四届全国中药和天然药物学术研讨会暨第十三届中药全球化联盟大会 | 被引量 : 0次 | 上传用户:zchunhua3120
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Although ethanolic extract of Alpinia oxyphylla (AOE) has displayed promising protective effects against 6-hydroxydopamine (6-OHDA)-induced injury in PC12 cells and zebrafish dopaminergic neurons, its bioactive components have remained unknown.In this present study, we elucidated the synergistic neuroprotective effects of two polyphenols present in AOE;protocatechuic acid (PCA) enhanced the neuroprotective effect of chrysin in 6-OHDA-treated PC12 cells in vitro.
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