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There is a wide range of applications of radiofrequency ablation (RFA) for patients with hepatocellular carcinoma (HCC).Despite its favorable survival outcome, RFA is associated with various unresolved problems.Because of the high tumor recurrence after RFA, the impact of tumor recurrence pattern on long-term patients survival is poorly understood.It has been shown that patients with local or same segment intrahepatic recurrence had better overall survival than those with different segment intrahepatic recurrence or extrahepatic metastasis.The pattern of recurrence was the independent prognostic factor for overall survival after RFA.Effective treatment modalities were feasible in the majority of patients with local or same segment intrahepatic recurrence.