Nerve injury-induced epigenetic silencing of opioid receptors controlled by G9a in primary afferent

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户:AceAcer
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  Neuropathic pain,a distressing clinical condition,is hard to treat in part due to incompletely understanding nerve injury-induced changes in gene transcription and translation in first-order sensory neurons of dorsal root ganglion(DRG).DNA methylation gates gene expression.
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