B cells consistently represent abundant cellular components in tumors;however, direct evidence supporting a role for B cells in the immunopathogenesis of human cancers is lacking, as is specific knowl
Objective: To evaluate efficacy and safety of dendritic cells in combination with cytokine-induced killer cell treatment of patients with colorectal cancer.
Autophagy and tumor microenvironment have both been considered to be crucial for the tumor progression.However,little is known about the potential roles of microenvironment in the regulation and funct
Recent evidence suggests that immunological memory does not only consist of memory lymphocytes circulating through the body, but that distinct and prominent populations of memory lymphocytes reside in
Innate immunity consists of a cellular and a humoral arm.The long pentraxin PTX3 as originally cloned (cDNA and genomics, mouse and human) as an IL-1 inducible gene.
TRAF family member-associated NF-κB activator (TANK) is a scaffold protein that assembles into the IRF3/7-phosphor-ylating TBK1-IKKε complex, where it is involved in regulating phosphorylation of the