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5. The m6A RNA Methylation Enhances 6-phosphogluconate dehydrogenase Expression to Promote Lung Cancer

The m6A RNA Methylation Enhances 6-phosphogluconate dehydrogenase Expression to Promote Lung Cancer

来源 :中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议 | 被引量 : 0次 | 上传用户：Shan417

【摘 要】

：

　　6-phosphogluconate dehydrogenase(6PGD),the third enzyme in the oxidative pentose phosphate pathway(PPP)contributes to tumor growth.Our previous study showed

【作 者】

：

Hao Sheng Yanke Guo Zhen Li Xiaoya Zhang Zhaoliang Lu Qi Feng Ronghui Liang Yanping Li Leilei Li Jing Li Dan Li Shuangping Liu Shuai Zhang Changliang Shan 

【机 构】

：

TheFirstAffiliatedHospital,BiomedicalTranslationalResearchInstitute,GuangdongProvinceKeyLaboratoryof

【出 处】

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中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议

【发表日期】

：

2018年10期

【关键词】

：

6-phosphogluconate dehydrogenase RNA m6A modification metabolism oxidative pento 

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　　6-phosphogluconate dehydrogenase(6PGD),the third enzyme in the oxidative pentose phosphate pathway(PPP)contributes to tumor growth.Our previous study showed that lung cancer patients with higher 6PGD levels had worse survival outcomes compared with patients with lower 6PGD expression.

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