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目的 肾盂输尿管(上尿路)尿路上皮癌具有较强侵袭性,预后不佳.基于铂类药物的化疗效果有限.发展迅速的免疫检查点治疗可能为尿路上皮癌提供了新的治疗选择.Carcinoma of renal pelvic and ureter(upper urinary tract urothelial carcinoma)is likely to be highly invasive and the prognosis is poor.Chemotherapy based on platinum has effect,but somehow limited.The immunological checkpoint inhibitors therapy is promising and may provide a new therapeutic strategy for urothelial carcinoma.