【摘 要】
:
杂环烯酮缩胺的α-C的反应包括烷基化,芳基化,酰化,卤代,硝化等情况,但目前尚未见芳基硫化的报道。本文报道一个AgOAc促进的杂环烯酮缩胺直接亚磺酰化合成砜类化合物的方法,所合成的新型砜类化合物可用于抗肿瘤等药理活性筛选。
【机 构】
:
云南大学化学科学与工程学院 教育部自然资源药物化学重点实验室 昆明 650091
论文部分内容阅读
杂环烯酮缩胺的α-C的反应包括烷基化,芳基化,酰化,卤代,硝化等情况,但目前尚未见芳基硫化的报道。本文报道一个AgOAc促进的杂环烯酮缩胺直接亚磺酰化合成砜类化合物的方法,所合成的新型砜类化合物可用于抗肿瘤等药理活性筛选。
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