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目的:观察甲氨蝶呤联合米非司酮治疗异位妊娠疗效和预后分析。方法:选取我县2011年7月-2013年7月各医院收治的62位异位妊娠患者,随机分为两组:对照组31例,单用甲氨蝶呤治疗,观察组31例,采用甲氨蝶呤联合米非司酮治疗。观察和比较两组治疗有效率、不良反应发生率以及预后再次宫内受孕成功率。结果:观察组有效率为90.32%,不良反应发生率为16.13%。对照组有效率为70.96%,不良反应发生率为29.03%,两组相比,差异具有统计学意义(P<0.05),预后方面,两组再次宫内受孕成功率差异无统计学意义(P>0.05)。结论:甲氨蝶呤联合米非司酮治疗异位妊娠成功率较高,不良反应发生率较低,安全有效,预后良好,有很高的应用价值,值得临床进一步推广使用。
Objective: To observe the efficacy and prognosis of methotrexate combined with mifepristone in the treatment of ectopic pregnancy. Methods: Sixty-two patients with ectopic pregnancy admitted to our hospital from July 2011 to July 2013 were randomly divided into two groups: control group (n = 31), methotrexate alone (n = 31) and observation group (n = 31) Methotrexate combined with mifepristone treatment. Observe and compare the two groups of treatment efficiency, incidence of adverse reactions and prognosis of intrauterine pregnancy success rate again. Results: The effective rate of observation group was 90.32%, the incidence of adverse reactions was 16.13%. The effective rate of the control group was 70.96%, the incidence of adverse reactions was 29.03%, the difference between the two groups was statistically significant (P <0.05), the prognosis, the two groups again intrauterine pregnancy success rate was no significant difference (P > 0.05). Conclusion: The combination of methotrexate and mifepristone has a high success rate of ectopic pregnancy, low incidence of adverse reactions, safe and effective, good prognosis and high application value, which is worth further promotion in clinic.