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应用放射免疫分析(RIA)对56例肝细胞癌(HCC)患者,30例肝外恶性肿瘤患者和正常人的血清与唾液甲胎蛋白(AFP)含量进行测定,并对部分HCC患者唾液AFP含量动态观察,探讨唾液AFP含量对HCC诊断、疗效观察等临床价值。结果表明唾液AFP与血清AFP含量呈明显正相关(P<0.01),唾液AFP含量测定对HCC的诊断、疗效判断有临床价值。
Radioimmunoassay (RIA) was used to measure serum and salivary alpha-fetoprotein (AFP) levels in 56 patients with hepatocellular carcinoma (HCC) and 30 patients with extrahepatic malignancy and normal controls. Saliva AFP levels in some patients with HCC were measured. Dynamic observation, to explore the clinical value of salivary AFP content for HCC diagnosis, efficacy observation. The results showed that there was a positive correlation between salivary AFP and serum AFP levels (P<0.01). The determination of salivary AFP content has clinical value in the diagnosis and therapeutic evaluation of HCC.