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患者女,72岁。右耳前面部皮肤出现肿物伴渗血50天。60年前右耳前肿物处曾有外伤后破溃史,愈后留有瘢痕(7.0cm×5.0cm),50天前该处皮肤被耳环钩破,后结痂,但痂皮常被擦破,可见出血。皮肤科情况:瘢痕中间可见一圆柱状蚕豆大斑块,呈暗红色,基底部有红晕,表面凹凸不平,周边有渗血,结黄痂和血痂。皮损组织病理示:肿瘤细胞从表皮向真皮浸润性生长,可见细胞异型性、病理性核分裂相,部分区域可见导管样结构。免疫组化染色示导管样结构EMA和CEA阳性。诊断:瘢痕继发小汗腺汗孔癌。
Female patient, 72 years old. Right front ear skin with blood seepage for 50 days. 60 years ago, there was a history of post-traumatic rupture in the right anterior ear ear. The more the scar was left (7.0 cm × 5.0 cm), the skin was hooked and crusted after 50 days and the crust was often Rubbed, visible bleeding. Dermatology: scar visible in the middle of a cylindrical broad beans broad plaques, dark red, the Ministry of the Department of flush, uneven surface, peripheral bleeding, the junction of yellow scab and blood scab. Pathological lesions showed: tumor cells from the epidermis to the dermis infiltrative growth, showing cell atypia, pathological mitotic phase, visible duct-like structure in some areas. Immunohistochemical staining showed that the catheter-like structures were positive for EMA and CEA. Diagnosis: scar small sweat gland sweat pores.