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目的:观察奥美拉唑联合雷尼替丁对胃食管反流病的典型食管症状的临床疗效。方法:将60例胃食管反流病患者随机分为治疗组和对照组各30例,治疗组给予奥美拉唑联合雷尼替丁口服,对照组仅予奥美拉唑口服,观察两组治疗前后烧心和反流症状的改善情况;结果:治疗组烧心和反流症状的显效率及有效率明显高于对照组(P<0.01)。结论:奥美拉唑联合与雷尼替丁联合用药治疗胃食管反流病的临床疗效明显优于单独使用奥美拉唑。
Objective: To observe the clinical effects of omeprazole combined with ranitidine on typical esophageal symptoms of gastroesophageal reflux disease. Methods: 60 cases of gastroesophageal reflux disease were randomly divided into treatment group and control group of 30 cases, the treatment group omeprazole combined with ranitidine oral administration of only omeprazole orally, two groups were observed The improvement of heartburn and reflux symptoms before and after treatment were observed. Results: The effective rate and effective rate of heartburn and reflux were significantly higher in the treatment group than those in the control group (P <0.01). Conclusion: The clinical efficacy of omeprazole combined with ranitidine in the treatment of gastroesophageal reflux disease is superior to omeprazole alone.