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已经证明随体联合的频率与人类近端着丝粒染色体核仁形成区的阳性银染相关,并认为它们取决于有功能的核蛋白体基因的存在。本文研究了一个具多重变型—在染色体13,21和22上存在三个随体—的个体的近端着丝粒染色体的随体联合,以便(1)探讨确认的单个近端着丝粒染色体的随体联合(SA)与银染;(2)检验这些参数是否相关;(3)比较所鉴定的染色体在银染时是参与随体联合还是散布在中期相中;(4)解释短臂结构变型间的关系。
The frequency of satellite association has been shown to correlate with positive silver staining of human proximal centromeric chromosomal nucleolar regions and they are believed to depend on the presence of functional ribosomal genes. In this paper we studied the satellite association of the proximal centromeric chromosomes of individuals with multiple variants with three subsites on chromosomes 13, 21 and 22 in order to (1) examine the identity of a single proximal centromeric chromosome (2) to test whether these parameters are relevant; (3) to compare whether the identified chromosomes are associated with the interspersed or dispersed in the metaphase during silver staining; and (4) to explain whether the short arm Relationship between structural variations.