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目的：探讨神经节细胞在暗视阈值反应（ｓｃｏｔｏｐｉｃｔｈｒｅｓｈｏｌｄｒｅｓｐｏｎｓｅ，ＳＴＲ）形成中的作用。方法：记录６只正常猫眼和４只视网膜光凝猫眼的ＳＴＲ。倍频ＹＡＧ固体激光环绕视乳头周围行视网膜光凝，光凝后分别于４、８和１６周记录闪光视觉诱发电位（ＦＶＥＰ）和系列光暗适应视网膜电图（ＥＲＧ），并于光凝后８、１６周取视网膜作光镜和透射电镜观察。记录１８名正常人和６例视神经萎缩患者的ＦＶＥＰ、系列光暗适应ＥＲＧ和ＳＴＲ。结果：光镜和透射电镜观察证实，视网膜光凝后神经节细胞逆行性萎缩。光凝后猫眼ＦＶＥＰ消失、ＳＴＲ在正常范围。视神经萎缩患者ＦＶＥＰ消失，ＳＴＲ和正常对照组无显著性差异。结论：神经节细胞在ＳＴＲ形成过程中不起作用，ＳＴＲ的细胞起源和神经节细胞无关。
Objective: To investigate the role of ganglion cells in the formation of scotopic threshold response (STR). Methods: The STR of 6 normal cats and 4 retinal photocoagulation cats were recorded. The octave YAG solid laser was used to wrap the retinal photocoagulation around the optic disc. After photocoagulation, flash visual evoked potentials (FVEP) and series of light dark adaptation electroretinogram (ERG) were recorded at 4, 8 and 16 weeks respectively. The retina was taken at 8 and 16 weeks for light and transmission electron microscopy. FVEP was recorded in 18 normal subjects and 6 patients with optic atrophy, and the series of light and dark adaptation to ERG and STR. Results: The light and transmission electron microscopy confirmed retrograde atrophy of retinal ganglion cells after photocoagulation. Catheter FVEP disappeared after photocoagulation, STR in the normal range. FVEP in patients with optic atrophy disappeared, STR and normal control group no significant difference. CONCLUSION: Ganglion cells have no role in the process of STR formation. The origin of STRs is not related to ganglion cells.